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eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function

As cells encounter adverse environmental conditions, such as hypoxia, oxidative stress or nutrient deprivation, they trigger stress response pathways to protect themselves until transient stresses have passed. Inhibition of translation is a key component of such cellular stress responses and mountin...

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Detalles Bibliográficos
Autores principales: Lyons, Shawn M, Kharel, Prakash, Akiyama, Yasutoshi, Ojha, Sandeep, Dave, Dhwani, Tsvetkov, Vladimir, Merrick, William, Ivanov, Pavel, Anderson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293036/
https://www.ncbi.nlm.nih.gov/pubmed/32374873
http://dx.doi.org/10.1093/nar/gkaa336