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Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
The TRM10 family of methyltransferases is responsible for the N(1)-methylation of purines at position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10-type enzymes, of which only the mitochondrial TRMT10C was previously characterized in detail, whereas the functional significa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293042/ https://www.ncbi.nlm.nih.gov/pubmed/32392304 http://dx.doi.org/10.1093/nar/gkaa353 |