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Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B

The TRM10 family of methyltransferases is responsible for the N(1)-methylation of purines at position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10-type enzymes, of which only the mitochondrial TRMT10C was previously characterized in detail, whereas the functional significa...

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Detalles Bibliográficos
Autores principales:	Vilardo, Elisa, Amman, Fabian, Toth, Ursula, Kotter, Annika, Helm, Mark, Rossmanith, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293042/ https://www.ncbi.nlm.nih.gov/pubmed/32392304 http://dx.doi.org/10.1093/nar/gkaa353

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