Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide

Elevated levels of plasma alpha1-antitrypsin (AAT) correlate with a poor prognosis of various cancers. Herein, we investigated effects of exogenous AAT on non-small lung cancer cell lines with high (H1975) and very low (H661) baseline expression of SERPINA1 gene encoding AAT protein. Comparison of c...

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Detalles Bibliográficos
Autores principales: Schwarz, Natalie, Tumpara, Srinu, Wrenger, Sabine, Ercetin, Evrim, Hamacher, Jürg, Welte, Tobias, Janciauskiene, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293251/
https://www.ncbi.nlm.nih.gov/pubmed/32533048
http://dx.doi.org/10.1038/s41598-020-66825-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293251/
https://www.ncbi.nlm.nih.gov/pubmed/32533048
http://dx.doi.org/10.1038/s41598-020-66825-w

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