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The interactions between cGAS-STING pathway and pathogens

Cytosolic DNA is an indicator of pathogen invasion or DNA damage. The cytosolic DNA sensor cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) detects DNA and then mediates downstream immune responses through the molecule stimulator of interferon genes (STING, also known a...

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Detalles Bibliográficos
Autores principales: Cheng, Zhangliang, Dai, Tong, He, Xuelin, Zhang, Zhengkui, Xie, Feng, Wang, Shuai, Zhang, Long, Zhou, Fangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293265/
https://www.ncbi.nlm.nih.gov/pubmed/32532954
http://dx.doi.org/10.1038/s41392-020-0198-7