Robust combination of liver stereotactic body radiotherapy modulates pharmacokinetics of sorafenib toward preferable parameters

To evaluate the effect and mechanism of radiotherapy (RT)–sorafenib pharmacokinetics (PK) in different regimens with conventional or high dose irradiation. Between February 2012 and December 2018, 43 patients with portal vein tumor thrombosis treated with sorafenib plus conventional RT (58%) or ster...

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Detalles Bibliográficos
Autores principales: Hsieh, Chen-Hsi, Chen, Yu-Jen, Tsai, Tung-Hu, Wang, Li-Ying, Tai, Hung-Chi, Huang, Hsiang-Ling, Huang, Yu-Chuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293270/
https://www.ncbi.nlm.nih.gov/pubmed/32533042
http://dx.doi.org/10.1038/s41598-020-66583-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293270/
https://www.ncbi.nlm.nih.gov/pubmed/32533042
http://dx.doi.org/10.1038/s41598-020-66583-9

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