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Biochemical activity of RAGs is impeded by Dolutegravir, an HIV integrase inhibitor

HIV is a retrovirus that infects CD4(+) T lymphocytes in human beings and causes immunodeficiency. In the recent years, various therapies have been developed against HIV, including targeting the HIV specific protein, integrase, responsible for integration of HIV cDNA into host DNA. Although, integra...

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Detalles Bibliográficos
Autores principales: Nilavar, Namrata M., Paranjape, Amita M., Raghavan, Sathees C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293277/
https://www.ncbi.nlm.nih.gov/pubmed/32566255
http://dx.doi.org/10.1038/s41420-020-0281-4