Cargando…
Biochemical activity of RAGs is impeded by Dolutegravir, an HIV integrase inhibitor
HIV is a retrovirus that infects CD4(+) T lymphocytes in human beings and causes immunodeficiency. In the recent years, various therapies have been developed against HIV, including targeting the HIV specific protein, integrase, responsible for integration of HIV cDNA into host DNA. Although, integra...
Autores principales: | Nilavar, Namrata M., Paranjape, Amita M., Raghavan, Sathees C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293277/ https://www.ncbi.nlm.nih.gov/pubmed/32566255 http://dx.doi.org/10.1038/s41420-020-0281-4 |
Ejemplares similares
-
HIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination
por: Nishana, Mayilaadumveettil, et al.
Publicado: (2017) -
Nonamer dependent RAG cleavage at CpGs can explain mechanism of chromosomal translocations associated to lymphoid cancers
por: Paranjape, Amita M., et al.
Publicado: (2022) -
Characterization of G-quadruplex antibody reveals differential specificity for G4 DNA forms
por: Javadekar, Saniya M, et al.
Publicado: (2020) -
7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
por: Ziegler, Robert E., et al.
Publicado: (2018) -
Biochemical Characterization of Nonamer Binding Domain of RAG1 Reveals its Thymine Preference with Respect to Length and Position
por: Raveendran, Deepthi, et al.
Publicado: (2016)