Genetic variations in catechol-O-methyltransferase gene are associated with levodopa response variability in Chinese patients with Parkinson’s disease

Catechol-O-methyltransferase (COMT) is one of the main enzymes in dopamine metabolism and is reported to be associated with susceptibility to Parkinson’s disease (PD) and pharmacotherapy. However, researchers mostly focus on the most common polymorphism, rs4680. In this case-control study, we invest...

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Detalles Bibliográficos
Autores principales: Zhao, Cuiping, Wang, Yihua, Zhang, Bin, Yue, Yaoxian, Zhang, Jianyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293305/
https://www.ncbi.nlm.nih.gov/pubmed/32533012
http://dx.doi.org/10.1038/s41598-020-65332-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293305/
https://www.ncbi.nlm.nih.gov/pubmed/32533012
http://dx.doi.org/10.1038/s41598-020-65332-2

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