Eudragit(®)-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers

AIM: Etoricoxib is a selective inhibitor of COX-2 enzyme. It is proposed as a potent anti-inflammatory drug intended for the control of irritable bowel syndrome. The current work aimed at developing etoricoxib-loaded nanoparticles for colon- targeting. MATERIALS AND METHODS: PLGA nanoparticles were...

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Detalles Bibliográficos
Autores principales: El-Maghawry, Enas, Tadros, Mina I, Elkheshen, Seham A, Abd-Elbary, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293536/
https://www.ncbi.nlm.nih.gov/pubmed/32606658
http://dx.doi.org/10.2147/IJN.S244124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293536/
https://www.ncbi.nlm.nih.gov/pubmed/32606658
http://dx.doi.org/10.2147/IJN.S244124

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