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Eudragit(®)-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers
AIM: Etoricoxib is a selective inhibitor of COX-2 enzyme. It is proposed as a potent anti-inflammatory drug intended for the control of irritable bowel syndrome. The current work aimed at developing etoricoxib-loaded nanoparticles for colon- targeting. MATERIALS AND METHODS: PLGA nanoparticles were...
Autores principales: | El-Maghawry, Enas, Tadros, Mina I, Elkheshen, Seham A, Abd-Elbary, Ahmed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293536/ https://www.ncbi.nlm.nih.gov/pubmed/32606658 http://dx.doi.org/10.2147/IJN.S244124 |
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