Cargando…
Nucleation seed size determines amyloid clearance and establishes a barrier to prion appearance in yeast
Amyloid appearance is a rare event that is promoted in the presence of other aggregated proteins. These aggregates were thought to act by templating the formation of an assembly-competent nucleation seed, but we find an unanticipated role for them in enhancing the persistence of amyloid after it ari...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293557/ https://www.ncbi.nlm.nih.gov/pubmed/32367069 http://dx.doi.org/10.1038/s41594-020-0416-6 |