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Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

INTRODUCTION: Extracellular vesicles (EVs) from human Alzheimer's disease (AD) biospecimens contain amyloid beta (Aβ) peptide and tau. While AD EVs are known to affect brain disease pathobiology, their biochemical and molecular characterizations remain ill defined. METHODS: EVs were isolated fr...

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Detalles Bibliográficos
Autores principales: Muraoka, Satoshi, DeLeo, Annina M., Sethi, Manveen K., Yukawa‐Takamatsu, Kayo, Yang, Zijian, Ko, Jina, Hogan, John D., Ruan, Zhi, You, Yang, Wang, Yuzhi, Medalla, Maria, Ikezu, Seiko, Chen, Mei, Xia, Weiming, Gorantla, Santhi, Gendelman, Howard E., Issadore, David, Zaia, Joseph, Ikezu, Tsuneya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293582/
https://www.ncbi.nlm.nih.gov/pubmed/32301581
http://dx.doi.org/10.1002/alz.12089