Inhibition of eIF2α Dephosphorylation Protects Hepatocytes from Apoptosis by Alleviating ER Stress in Acute Liver Injury

OBJECTIVES: Protein kinase R-like ER kinase (PERK)/eukaryotic initiation factor 2 alpha (eIF2α) is an important factor along the main pathways for endoplasmic reticulum (ER) stress-mediated apoptosis. In this study, we investigated the effects of eIF2α phosphorylation on hepatocyte apoptosis and the...

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Detalles Bibliográficos
Autores principales: Tang, Yong-Jing, Chen, Huan, Yi, Yu, Chen, Gui-Mei, Yang, Fang-Wan, Li, Ying, Tian, Ren-Dong, Huang, Wen-Ge, Cheng, Qi-Jiao, He, Yi-Huai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293739/
https://www.ncbi.nlm.nih.gov/pubmed/32566674
http://dx.doi.org/10.1155/2020/2626090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293739/
https://www.ncbi.nlm.nih.gov/pubmed/32566674
http://dx.doi.org/10.1155/2020/2626090

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