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Molecular mechanisms involved in high glucose‐induced valve calcification in a 3D valve model with human valvular cells

Calcific aortic valve disease (CAVD)—the most common valvular heart disease—is accelerated in diabetes and has no pharmacotherapy. Although it is known that early CAVD is associated with inflammation and osteogenesis, the molecular mechanisms involved in diabetes‐associated CAVD still need to be unc...

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Detalles Bibliográficos
Autores principales: Vadana, Mihaela, Cecoltan, Sergiu, Ciortan, Letitia, Macarie, Razvan D., Tucureanu, Monica M., Mihaila, Andreea C., Droc, Ionel, Butoi, Elena, Manduteanu, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294117/
https://www.ncbi.nlm.nih.gov/pubmed/32307869
http://dx.doi.org/10.1111/jcmm.15277