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Tissue‐selective regulation of protein homeostasis and unfolded protein response signalling in sporadic ALS

Amyotrophic lateral sclerosis (ALS) is a disorder that affects motor neurons in motor cortex and spinal cord, and the degeneration of both neuronal populations is a critical feature of the disease. Abnormalities in protein homeostasis (proteostasis) are well established in ALS. However, they have be...

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Detalles Bibliográficos
Autores principales: Montibeller, Luigi, Tan, Li Yi, Kim, Joo Kyung, Paul, Praveen, de Belleroche, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294118/
https://www.ncbi.nlm.nih.gov/pubmed/32324341
http://dx.doi.org/10.1111/jcmm.15170