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Hypermethylation‐mediated down‐regulation of lncRNA TBX5‐AS1:2 in Tetralogy of Fallot inhibits cell proliferation by reducing TBX5 expression

Tetralogy of Fallot (TOF) is the most common complex congenital heart disease (CHD) with uncertain cause. Although long non‐coding RNAs (lncRNAs) have been implicated in heart development and several CHDs, their role in TOF is not well understood. This study aimed to investigate how dysregulated lnc...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Chen, Shiyu, Hao, Lili, Sheng, Wei, Chen, WeiCheng, Ma, Xiaojing, Zhang, Bowen, Ma, Duan, Huang, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294119/
https://www.ncbi.nlm.nih.gov/pubmed/32368852
http://dx.doi.org/10.1111/jcmm.15298