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RNA demethylase ALKBH5 promotes ovarian carcinogenesis in a simulated tumour microenvironment through stimulating NF‐κB pathway

Methylation is the main form of RNA modification. N6‐methyladenine (m6A) regulates the splicing and translation of mRNA. Alk B homologue 5 (ALKBH5) participates in the biological regulation of various cancers. However, its role in ovarian carcinogenesis has not been unveiled. In the present study, A...

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Detalles Bibliográficos
Autores principales: Jiang, Yi, Wan, Yicong, Gong, Mi, Zhou, Shulin, Qiu, Jiangnan, Cheng, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294121/
https://www.ncbi.nlm.nih.gov/pubmed/32329191
http://dx.doi.org/10.1111/jcmm.15228