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Loganin alleviates testicular damage and germ cell apoptosis induced by AGEs upon diabetes mellitus by suppressing the RAGE/p38MAPK/NF‐κB pathway

Diabetes mellitus (DM) damages male reproduction at multiple levels, such as endocrine secretion, spermatogenesis and penile erection. We herein investigated the protective effects and mechanism of loganin targeting the advanced glycation end products (AGEs)/receptor for AGEs (RAGE)/p38 mitogen‐acti...

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Detalles Bibliográficos
Autores principales: Chen, Yuping, Jiao, Ni, Jiang, Ming, Liu, Liping, Zhu, Yihui, Wu, Hongyan, Chen, Jing, Fu, Yingxue, Du, Qiu, Xu, Huiqin, Sun, Jihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294151/
https://www.ncbi.nlm.nih.gov/pubmed/32307890
http://dx.doi.org/10.1111/jcmm.15198