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Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents

The parasitic disease malaria places almost half of the world’s population at risk of infection and is responsible for more than 400,000 deaths each year. The first-line treatment, artemisinin combination therapies (ACT) regimen, is under threat due to emerging resistance of Plasmodium falciparum st...

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Detalles Bibliográficos
Autores principales: Van de Walle, Tim, Boone, Maya, Van Puyvelde, Julie, Combrinck, Jill, Smith, Peter J., Chibale, Kelly, Mangelinckx, Sven, D’hooghe, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294232/
https://www.ncbi.nlm.nih.gov/pubmed/32408064
http://dx.doi.org/10.1016/j.ejmech.2020.112330