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Muscarinic Modulation of SK2-Type K(+) Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex
Muscarinic acetylcholine receptors (mAChRs) inhibit small-conductance calcium-activated K(+) channels (SK channels) and enhance synaptic weight via this mechanism. SK channels are also involved in activity-dependent plasticity of membrane excitability (“intrinsic plasticity”). Here, we investigate w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294454/ https://www.ncbi.nlm.nih.gov/pubmed/32005752 http://dx.doi.org/10.1523/ENEURO.0453-19.2020 |