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Muscarinic Modulation of SK2-Type K(+) Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex

Muscarinic acetylcholine receptors (mAChRs) inhibit small-conductance calcium-activated K(+) channels (SK channels) and enhance synaptic weight via this mechanism. SK channels are also involved in activity-dependent plasticity of membrane excitability (“intrinsic plasticity”). Here, we investigate w...

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Detalles Bibliográficos
Autores principales: Gill, Daniel F., Hansel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294454/
https://www.ncbi.nlm.nih.gov/pubmed/32005752
http://dx.doi.org/10.1523/ENEURO.0453-19.2020