Differential Stability of miR-9-5p and miR-9-3p in the Brain Is Determined by Their Unique Cis- and Trans-Acting Elements

microRNAs (miRs) are fundamental regulators of protein coding genes. In the CNS, miR-9 is highly enriched and critical for neuronal development and function. Mature miRs are derived from a duplex precursor, and the -5p strand (“guide”) is preferentially incorporated into an RNA-induced silencing com...

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Detalles Bibliográficos
Autores principales: Kim, C.K., Asimes, A., Zhang, M., Son, B.T., Kirk, J.A., Pak, T.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294468/
https://www.ncbi.nlm.nih.gov/pubmed/32376600
http://dx.doi.org/10.1523/ENEURO.0094-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294468/
https://www.ncbi.nlm.nih.gov/pubmed/32376600
http://dx.doi.org/10.1523/ENEURO.0094-20.2020

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