β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways

BACKGROUND: The most common chemotherapeutic drug for triple-negative breast cancer (TNBC) treatment is 5-fluorouracil (5-FU), but its therapeutic index is low due to its toxicity. β-Elemene (ELE) possesses antitumor activity against different cancers, but it has never been used in combination with...

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Detalles Bibliográficos
Autores principales: Su, Pengyu, Ahmad, Bashir, Zou, Kun, Zou, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294576/
https://www.ncbi.nlm.nih.gov/pubmed/32606741
http://dx.doi.org/10.2147/OTT.S242820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294576/
https://www.ncbi.nlm.nih.gov/pubmed/32606741
http://dx.doi.org/10.2147/OTT.S242820

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