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Favorable efficacy of rituximab in ANCA-associated vasculitis patients with excessive B cell differentiation

OBJECTIVES: B cell depletion by rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV). However, peripheral B cell phenotypes and the selection criteria for RTX therapy in AAV remain unclear. METHODS: Phenotypic characterization of c...

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Detalles Bibliográficos
Autores principales: Miyazaki, Yusuke, Nakayamada, Shingo, Kubo, Satoshi, Ishikawa, Yuichi, Yoshikawa, Maiko, Sakata, Kei, Iwata, Shigeru, Miyagawa, Ippei, Nakano, Kazuhisa, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294638/
https://www.ncbi.nlm.nih.gov/pubmed/32539843
http://dx.doi.org/10.1186/s13075-020-02215-x