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Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia

BACKGROUND: Ischemic stroke poses a severe risk to human health worldwide, and currently, clinical therapies for the disease are limited. Delta opioid receptor (DOR)-mediated neuroprotective effects against ischemia have attracted increasing attention in recent years. Our previous studies revealed t...

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Detalles Bibliográficos
Autores principales: Lai, Zelin, Gu, Lingling, Yu, Lu, Chen, Huifen, Yu, Zhenhua, Zhang, Cheng, Xu, Xiaoqing, Zhang, Mutian, Zhang, Min, Ma, Mingliang, Zhao, Zheng, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294676/
https://www.ncbi.nlm.nih.gov/pubmed/32549974
http://dx.doi.org/10.1186/s13578-020-00441-z