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Melanocortin-3 receptors expressed on agouti-related peptide neurons inhibit feeding behavior in female mice.

OBJECTIVE: Activation of hypothalamic agouti-related peptide (AgRP)(+ve) neurons during energy deficit is a negative valence signal, rapidly activating food seeking behaviors. This study examined the roles of MC3Rs expressed by AgRP(+ve) neurons. METHODS: AgRP-MC3R mice expressing MC3Rs selectively...

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Detalles Bibliográficos
Autores principales: Girardet, Clemence, Marks, Daniel L., Butler, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294842/
https://www.ncbi.nlm.nih.gov/pubmed/30426710
http://dx.doi.org/10.1002/oby.22306