The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells

High-dose synthetic estrogen therapy was the standard treatment of advanced breast cancer for three decades until the discovery of tamoxifen. A range of substituted triphenylethylene synthetic estrogens and diethylstilbestrol were used. It is now known that low doses of estrogens can cause apoptosis...

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Detalles Bibliográficos
Autores principales: Maximov, Philipp Y., Abderrahman, Balkees, Hawsawi, Yousef M., Chen, Yue, Foulds, Charles E., Jain, Antrix, Malovannaya, Anna, Fan, Ping, Curpan, Ramona F., Han, Ross, Fanning, Sean W., Broom, Bradley M., Quintana Rincon, Daniela M., Greenland, Jeffery A., Greene, Geoffrey L., Jordan, V. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294906/
https://www.ncbi.nlm.nih.gov/pubmed/32362585
http://dx.doi.org/10.1124/mol.120.119776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294906/
https://www.ncbi.nlm.nih.gov/pubmed/32362585
http://dx.doi.org/10.1124/mol.120.119776

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