Cargando…

Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis

Diabetes-mediated hyperglycemia is a major risk factor for renal fibrosis, resulting in the development of chronic kidney diseases. To address this issue, the effect of melatonin, which has an antioxidative potential, on renal fibrosis in human renal proximal tubule epithelial cells under high gluco...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Yong-Seok, Yoon, Yeo Min, Go, Gyeongyun, Lee, Jun Hee, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294914/
https://www.ncbi.nlm.nih.gov/pubmed/32547319
http://dx.doi.org/10.7150/ijms.42603