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Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis
Diabetes-mediated hyperglycemia is a major risk factor for renal fibrosis, resulting in the development of chronic kidney diseases. To address this issue, the effect of melatonin, which has an antioxidative potential, on renal fibrosis in human renal proximal tubule epithelial cells under high gluco...
Autores principales: | Han, Yong-Seok, Yoon, Yeo Min, Go, Gyeongyun, Lee, Jun Hee, Lee, Sang Hun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294914/ https://www.ncbi.nlm.nih.gov/pubmed/32547319 http://dx.doi.org/10.7150/ijms.42603 |
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