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Mitochondrial Transcription Factor A added to Osteocytes in a Stressed Environment has a Cytoprotective Effect

The main precipitant of glucocorticoid-associated femoral head osteonecrosis is widely accepted to be an ischemic-hypoxic event, with oxidative stress also as an underlying factor. Mitochondrial DNA is more vulnerable to oxidative injury than the nucleus, and mitochondrial transcription factor A (TF...

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Detalles Bibliográficos
Autores principales: Ueda, Shusuke, Shimasaki, Miyako, Ichiseki, Toru, Hirata, Hiroaki, kawahara, Norio, Ueda, Yoshimichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294917/
https://www.ncbi.nlm.nih.gov/pubmed/32547324
http://dx.doi.org/10.7150/ijms.45335