AKR1B10 Inhibitor Epalrestat Facilitates Sorafenib-Induced Apoptosis and Autophagy Via Targeting the mTOR Pathway in Hepatocellular Carcinoma

Sorafenib is the standard systemic treatment for advanced hepatocellular carcinoma (HCC), and improving its therapeutic effects is crucial for addressing cancer aggression. We previously reported that epalrestat, an aldo-keto reductase 1B10 inhibitor, enhanced sorafenib's inhibitory effects on...

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Detalles Bibliográficos
Autores principales: Geng, Nan, Jin, Yuanyuan, Li, Yurong, Zhu, Shixuan, Bai, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294918/
https://www.ncbi.nlm.nih.gov/pubmed/32547320
http://dx.doi.org/10.7150/ijms.42956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294918/
https://www.ncbi.nlm.nih.gov/pubmed/32547320
http://dx.doi.org/10.7150/ijms.42956

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