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Identification of the key genes and microRNAs in adult acute myeloid leukemia with FLT3 mutation by bioinformatics analysis

Background: Associated with poor prognosis, FMS-like tyrosine kinase 3 (FLT3) mutation appeared frequently in acute myeloid leukemia (AML). Herein, we aimed to identify the key genes and miRNAs involved in adult AML with FLT3 mutation and find possible therapeutic targets for improving treatment. Ma...

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Detalles Bibliográficos
Autores principales: Chen, Shuyi, Chen, Yimin, Zhu, Zhiguo, Tan, Huo, Lu, Jielun, Qin, Pengfei, Xu, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294926/
https://www.ncbi.nlm.nih.gov/pubmed/32547322
http://dx.doi.org/10.7150/ijms.46441