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R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo

Introduction: Cell therapy and tissue engineering has recently emerged as a new option for short bowel syndrome (SBS) treatment, generating tissue engineered small intestine (TESI) from organoid units (OU) and biodegradable scaffolds. The recombinant human R-Spondin 1 (rhRSPO1) protein may be a key...

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Detalles Bibliográficos
Autores principales: Levin, Gabriel, Zuber, Samuel M., Squillaro, Anthony I., Sogayar, Mari Cleide, Grikscheit, Tracy C., Carreira, Ana Claudia O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295003/
https://www.ncbi.nlm.nih.gov/pubmed/32582652
http://dx.doi.org/10.3389/fbioe.2020.00476