Cargando…
R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo
Introduction: Cell therapy and tissue engineering has recently emerged as a new option for short bowel syndrome (SBS) treatment, generating tissue engineered small intestine (TESI) from organoid units (OU) and biodegradable scaffolds. The recombinant human R-Spondin 1 (rhRSPO1) protein may be a key...
Autores principales: | Levin, Gabriel, Zuber, Samuel M., Squillaro, Anthony I., Sogayar, Mari Cleide, Grikscheit, Tracy C., Carreira, Ana Claudia O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295003/ https://www.ncbi.nlm.nih.gov/pubmed/32582652 http://dx.doi.org/10.3389/fbioe.2020.00476 |
Ejemplares similares
-
Production, purification and characterization of recombinant human R-spondin1 (RSPO1) protein stably expressed in human HEK293 cells
por: Levin, Gabriel, et al.
Publicado: (2020) -
R-Spondin1 enhances wnt signaling and decreases weight loss in short bowel syndrome zebrafish
por: Maselli, Kathryn M., et al.
Publicado: (2021) -
Reversing Epithelial Polarity in Pluripotent Stem Cell-Derived Intestinal Organoids
por: Kakni, Panagiota, et al.
Publicado: (2022) -
Engineering Organoid Vascularization
por: Grebenyuk, Sergei, et al.
Publicado: (2019) -
Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism – Update to the Human Model and Expansion of Applications
por: Zietek, Tamara, et al.
Publicado: (2020)