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Aggregation pathways of human γ D crystallin induced by metal ions revealed by time dependent methods

Cataract formation is a slow accumulative process due to protein aggregates promoted by different factors over time. Zinc and copper ions have been reported to induce the formation of aggregates opaque to light in the human gamma D crystallin (HγD) in a concentration and temperature dependent manner...

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Detalles Bibliográficos
Autores principales: Fernández-Silva, Arline, French-Pacheco, Leidys, Rivillas-Acevedo, Lina, Amero, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295030/
https://www.ncbi.nlm.nih.gov/pubmed/32566392
http://dx.doi.org/10.7717/peerj.9178