Proinflammatory macrophage-derived microvesicles exhibit tumor tropism dependent on CCL2/CCR2 signaling axis and promote drug delivery via SNARE-mediated membrane fusion

Background: Exosome (Exo)-based chemotherapeutic drug delivery systems have been extensively investigated; however, the therapeutic potential of other subtypes of extracellular vesicles (EVs), in particular microvesicles (MiV), seem to be overlooked. Moreover, despite a general agreement on organ tr...

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Detalles Bibliográficos
Autores principales: Guo, Ling, Zhang, Ye, Wei, Runxiu, Zhang, Xiaochen, Wang, Cuifeng, Feng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295053/
https://www.ncbi.nlm.nih.gov/pubmed/32550891
http://dx.doi.org/10.7150/thno.45528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295053/
https://www.ncbi.nlm.nih.gov/pubmed/32550891
http://dx.doi.org/10.7150/thno.45528

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