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Therapeutic potential of a TrkB agonistic antibody for Alzheimer's disease

Repeated failures of “Aβ-lowering” therapies call for new targets and therapeutic approaches for Alzheimer's disease (AD). We propose to treat AD by halting neuronal death and repairing synapses using a BDNF-based therapy. To overcome the poor druggability of BDNF, we have developed an agonisti...

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Detalles Bibliográficos
Autores principales:	Wang, Shudan, Yao, Hongyang, Xu, Yihua, Hao, Rui, Zhang, Wen, Liu, Hang, Huang, Ying, Guo, Wei, Lu, Bai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295064/ https://www.ncbi.nlm.nih.gov/pubmed/32550908 http://dx.doi.org/10.7150/thno.44165

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