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Experimental determination of the force of malaria infection reveals a non-linear relationship to mosquito sporozoite loads

Plasmodium sporozoites are the infective stage of the malaria parasite. Though this is a bottleneck for the parasite, the quantitative dynamics of transmission, from mosquito inoculation of sporozoites to patent blood-stage infection in the mammalian host, are poorly understood. Here we utilize a ro...

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Detalles Bibliográficos
Autores principales: Aleshnick, Maya, Ganusov, Vitaly V., Nasir, Gibran, Yenokyan, Gayane, Sinnis, Photini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295235/
https://www.ncbi.nlm.nih.gov/pubmed/32453765
http://dx.doi.org/10.1371/journal.ppat.1008181