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Automated analysis of immunosequencing datasets reveals novel immunoglobulin D genes across diverse species

Immunoglobulin genes are formed through V(D)J recombination, which joins the variable (V), diversity (D), and joining (J) germline genes. Since variations in germline genes have been linked to various diseases, personalized immunogenomics focuses on finding alleles of germline genes across various p...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Vinnu, Franceschetti, Massimo, Rao, Ramesh, Pevzner, Pavel A., Safonova, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295240/
https://www.ncbi.nlm.nih.gov/pubmed/32339161
http://dx.doi.org/10.1371/journal.pcbi.1007837