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Automated analysis of immunosequencing datasets reveals novel immunoglobulin D genes across diverse species
Immunoglobulin genes are formed through V(D)J recombination, which joins the variable (V), diversity (D), and joining (J) germline genes. Since variations in germline genes have been linked to various diseases, personalized immunogenomics focuses on finding alleles of germline genes across various p...
Autores principales: | Bhardwaj, Vinnu, Franceschetti, Massimo, Rao, Ramesh, Pevzner, Pavel A., Safonova, Yana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295240/ https://www.ncbi.nlm.nih.gov/pubmed/32339161 http://dx.doi.org/10.1371/journal.pcbi.1007837 |
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