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A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans ass...

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Detalles Bibliográficos
Autores principales: Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H. M., Astrup, Arne, Hager, Jörg, Davison, Anthony C., Valsesia, Armand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295243/
https://www.ncbi.nlm.nih.gov/pubmed/32492067
http://dx.doi.org/10.1371/journal.pcbi.1007882