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A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma
Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans ass...
Autores principales: | Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H. M., Astrup, Arne, Hager, Jörg, Davison, Anthony C., Valsesia, Armand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295243/ https://www.ncbi.nlm.nih.gov/pubmed/32492067 http://dx.doi.org/10.1371/journal.pcbi.1007882 |
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