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Dynamical network analysis reveals key microRNAs in progressive stages of lung cancer

Non-coding RNAs are fundamental to the competing endogenous RNA (CeRNA) hypothesis in oncology. Previous work focused on static CeRNA networks. We construct and analyze CeRNA networks for four sequential stages of lung adenocarcinoma (LUAD) based on multi-omics data of long non-coding RNAs (lncRNAs)...

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Detalles Bibliográficos
Autores principales: Kong, Chao, Yao, Yu-Xiang, Bing, Zhi-Tong, Guo, Bing-Hui, Huang, Liang, Huang, Zi-Gang, Lai, Ying-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295246/
https://www.ncbi.nlm.nih.gov/pubmed/32428028
http://dx.doi.org/10.1371/journal.pcbi.1007793