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Stromal LAG-3(+) cells infiltration defines poor prognosis subtype muscle-invasive bladder cancer with immunoevasive contexture
BACKGROUND: Lymphocyte activation gene 3 (LAG-3) is a promising immune checkpoint therapeutic target being evaluated in clinical trials. We assessed the LAG-3(+) cells distribution, its association with clinical outcomes and immune contexture and its role in the landscape of muscle-invasive bladder...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295439/ https://www.ncbi.nlm.nih.gov/pubmed/32540859 http://dx.doi.org/10.1136/jitc-2020-000651 |