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IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment

BACKGROUND: As the immune system is compromised in patients with cancer, therapeutic strategies to stimulate immunity appear promising, to avoid relapse and increase long-term overall survival. Interleukin-15 (IL-15) has similar properties to IL-2, but does not cause activation-induced cell death no...

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Detalles Bibliográficos
Autores principales: Desbois, Mélanie, Béal, Coralie, Charrier, Mélinda, Besse, Benjamin, Meurice, Guillaume, Cagnard, Nicolas, Jacques, Yannick, Béchard, David, Cassard, Lydie, Chaput, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295443/
https://www.ncbi.nlm.nih.gov/pubmed/32532840
http://dx.doi.org/10.1136/jitc-2020-000632