Microneutralization assay titer correlates analysis in two phase 3 trials of the CYD-TDV tetravalent dengue vaccine in Asia and Latin America

We previously showed that Month 13 50% plaque reduction neutralization test (PRNT(50)) neutralizing antibody (nAb) titers against dengue virus (DENV) correlated with vaccine efficacy (VE) of CYD-TDV against symptomatic, virologically-confirmed dengue (VCD) in the CYD14 and CYD15 Phase 3 trials. Whil...

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Detalles Bibliográficos
Autores principales: Carpp, Lindsay N., Fong, Youyi, Bonaparte, Matthew, Moodie, Zoe, Juraska, Michal, Huang, Ying, Price, Brenda, Zhuang, Yingying, Shao, Jason, Zheng, Lingyi, Chambonneau, Laurent, Small, Robert, Sridhar, Saranya, DiazGranados, Carlos A., Gilbert, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295445/
https://www.ncbi.nlm.nih.gov/pubmed/32542024
http://dx.doi.org/10.1371/journal.pone.0234236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295445/
https://www.ncbi.nlm.nih.gov/pubmed/32542024
http://dx.doi.org/10.1371/journal.pone.0234236

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