Chromosome organization by one-sided and two-sided loop extrusion

SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops. Modeling assuming two-sided loop extrusion reproduces key features of chromatin organization acros...

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Detalles Bibliográficos
Autores principales: Banigan, Edward J, van den Berg, Aafke A, Brandão, Hugo B, Marko, John F, Mirny, Leonid A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295573/
https://www.ncbi.nlm.nih.gov/pubmed/32250245
http://dx.doi.org/10.7554/eLife.53558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295573/
https://www.ncbi.nlm.nih.gov/pubmed/32250245
http://dx.doi.org/10.7554/eLife.53558

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