Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway

Glucocorticoids (GCs) act through the glucocorticoid receptor (GR, also known as NR3C1) to regulate immunity, energy metabolism and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcriptio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kershaw, Stephen, Morgan, David J., Boyd, James, Spiller, David G., Kitchen, Gareth, Zindy, Egor, Iqbal, Mudassar, Rattray, Magnus, Sanderson, Christopher M., Brass, Andrew, Jorgensen, Claus, Hussell, Tracy, Matthews, Laura C., Ray, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295589/
https://www.ncbi.nlm.nih.gov/pubmed/32381682
http://dx.doi.org/10.1242/jcs.242842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295589/
https://www.ncbi.nlm.nih.gov/pubmed/32381682
http://dx.doi.org/10.1242/jcs.242842

Ejemplares similares