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Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway
Glucocorticoids (GCs) act through the glucocorticoid receptor (GR, also known as NR3C1) to regulate immunity, energy metabolism and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcriptio...
Autores principales: | Kershaw, Stephen, Morgan, David J., Boyd, James, Spiller, David G., Kitchen, Gareth, Zindy, Egor, Iqbal, Mudassar, Rattray, Magnus, Sanderson, Christopher M., Brass, Andrew, Jorgensen, Claus, Hussell, Tracy, Matthews, Laura C., Ray, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295589/ https://www.ncbi.nlm.nih.gov/pubmed/32381682 http://dx.doi.org/10.1242/jcs.242842 |
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