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miR-137 targets the inhibition of TCF4 to reverse the progression of osteoarthritis through the AMPK/NF-κB signaling pathway

Purpose: To explore the regulatory mechanism of miR-137 and transcription factor 4 (TCF4) in the progression of osteoarthritis (OA). Patients and Methods: The expressions of miR-137 and TCF4 were detected in OA cartilage tissue, chondrocytes and OA rat cartilage tissue. miR-137 and TCF4 were up-regu...

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Detalles Bibliográficos
Autores principales: Wang, Jinyu, Fang, Liming, Ye, Lili, Ma, Shiliang, Huang, Haoran, Lan, Xiaoquan, Ma, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295621/
https://www.ncbi.nlm.nih.gov/pubmed/32432314
http://dx.doi.org/10.1042/BSR20200466